I used to use Natural Advantage. It worked on my skin. Nobody believed that I was in my late 50's. I was 62 when I stopped. I just couldn't afford it anymore after I retired. I now use hyauluric acid and vitamin C. It is a lot cheaper. Natural Advantage was the best, ever. I would go back to it if I could afford to. I am sure that it depends on how damaged your skin is when you start using the product as to how quickly it begin to show improvement.